Palmitoylcarnitine and tricarboxylic-acid-cycle oxidations

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Malonate inhibition of oxidations in the Krebs tricarboxylic acid cycle.

The inhibition of succinate oxidation by malonate is a well known phenomenon. Since the oxidation of succinate to fumarate is an integral part of the Krebs cycle of oxidations, it has been generally assumed that the inhibitory effect of malonate upon the oxidation of any member of the cycle is the result of the inhibition of the succinate to fumarate step. However, the present paper provides ev...

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Some aspects of tricarboxylic acid-cycle activity during differentiation and aging in Dictyostelium discoideum were examined. The concentrations of glutamate, aspartate, alanine, citrate, 2-oxoglutarate, succinate, fumarate, malate, oxaloacetate, pyruvate and acetyl-CoA were determined at four stages over the course of differentiation. The rate of 02 utilization was also determined over differe...

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Tricarboxylic Acid Cycle in Pseudomonas Aeruginosa”

During the past few years scattered information has appeared which indicates that at least some bacteria probably possess a tricarboxylic acid cycle. Lockwood and Stodola found that Pseudomonas jluorescens formed considerable quantities of a-ketoglutaric acid when growing on a glucose medium under conditions of intense aeration (1). Ajl and Werkman found evidence for at least parts of the conve...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1969

ISSN: 0014-5793

DOI: 10.1016/0014-5793(69)80043-8